Anti-obesity drug Reductil. Reductil capsules and their packaging. Reductil, whose name is sibutramine, is an anti-obesity drug. It works by blocking the reabsorption of the neurotransmitters serotonin and norepinephrine. An increase in these chemicals in the brain suppresses appetite.
Reductil 15mg Capsule in Pakistan is a medication that assists with weight loss by altering neurotransmitters within the brain. Neurotransmitters are chemicals that are produced and released by nerves in order to communicate with other nerves. Release neurotransmitters may attach to other nerves or they may be take up again by the nerves that release them, a process terms re-uptake. Reductil blocks the re-uptake of the neurotransmitters dopamine, nor-epinephrine, and serotonin. Blocking the re-uptake of neurotransmitters alters the balance of neurotransmitters within the nerve cells and thereby affect nerve function and interaction. Patients taking sibutramine may achieve a 5-10% reduction from their baseline weight. Additionally, Reductil assisted weight loss has been accompanied by improvement in blood lipids (e.g, cholesterol). Reductil was approved by the FDA in 1997.
Sibutramine is use for weight loss in conjunction with a low calorie diet. Specific populations for whom the medication is recommend are those with an initial body mass index of more than 30 kg/m2 (27 mg/m2 if they also have other risk factors such as diabetes mellitus, high cholesterol or hypertension).
Sibutramine is take once daily, generally in the morning. Therapy usually is starts with one 10mg tablet per day. The dose may be increase to 15mg by the physician after several weeks to achieve the desired effect. Doses of up to 60mg have been studied. Sibutramine may be taken with or without food.
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Reductil 15mg (sibutramine) is unsafe to use in pregnancy. May cause excessive drowsiness and calmness with alcohol. May cause side effects which could affect your ability to drive.
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